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GLOBAL
OBSERVATORY
OF LONG-TERM
CARE

Part of the International Long-Term Care Policy Network (ILPN)

 

Suvarna Alladi

National Institute of Mental Health and Neurosciences

Suvarna Alladi

Suvarna Alladi is Professor and Head of Dept of Neurology, at the National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India. Dr Alladi specializes in cognitive neurology and started one of the first Memory Clinics in the country in Hyderabad, and now at NIMHANS coordinates a large multidisciplinary specialist service that provides comprehensive treatment and support for persons living with dementia and their families. Dr Alladi’s work focuses on investigating the complex influence of life-course experiences especially bilingualism, education, social engagement and skills, on developing resilience against dementia. To overcome the limited availability of diagnostic tests for dementia in diverse linguistic and educational contexts, she coordinated a country-wide effort to adapt and validate a neurocognitive battery: the “ICMR Neurocognitive toolbox’ for different Indian languages. Dr Alladi co-founded the NGO Alzheimer’s and Related Disorders Society, Hyderabad Deccan chapter that provides support, creates awareness and advocates for families of persons living with dementia. She represents perspectives of cognitive disorders from diverse contexts in international platforms as Past Chair, World Federation of Neurology, Specialty group on Aphasia Dementia & Cognitive disorders, Vice-Chair of the International Society to Advance Alzheimer’s Disease and Research, Alzheimer’s Association USA and is World Dementia Council Member. Dr Alladi is on the Lancet Commission for dementia prevention, intervention and care and was senior researcher on the STRiDE project

FURTHER INFORMATION

Countries India;
Topics Access to care; Care inequalities; Care innovations; Dementia care and support; Epidemiology and ageing trajectories; LTC systems in LMIC countries; New models of care; Person-centered care; Prevention and rehabilitation and LTC; Primary Health Care;
Methods Case studies; Document analysis; Expert consultations; Literature reviews and synthesis; Policy analysis; Quantitative data analysis; Research ethics; Theory of Change;
Role Research;
Interest Groups Strengthening Responses to Dementia;
GOOGLE SCHOLARhttps://scholar.google.ca/citations?user=aelKxWYAAAAJ&hl=en
Twitterhttps://twitter.com/alladi_suvarna
Research interests

Dementia, cognitive disorders, diagnosis, treatment, care, policy, prevention
Key publications

1. Bhattacharyya, B., Paplikar, A., Varghese, F., Das, G., Shukla, V., Arshad, F., … & Alladi, S. (2024). Illiterate Addenbrooke’s Cognitive Examination-III in Three Indian Languages: An Adaptation and Validation Study. Archives of Clinical Neuropsychology, acad106.

2. Baez, S., Alladi, S., & Ibanez, A. (2023). Global South research is critical for understanding brain health, ageing and dementia. Clinical and Translational Medicine, 13(11).

3. Khokhar, S. K., Kumar, M., Kumar, S., Manae, T., Thanissery, N., Ramakrishnan, S., Arshad, F., Nagaraj, C., Mangalore, S., Alladi, S. and Gandhi, T.K & Alzheimer’s Disease Neuroimaging Initiative. (2023). Alzheimer’s disease is associated with increased network assortativity: Evidence from metabolic connectivity. Brain Connectivity, 13(10), 610-620.

4. Franzen, S., Nuytemans, K., Bourdage, R., Caramelli, P., Ellajosyula, R., Finger, E., Illán-Gala. I., Loi, S.M., Morhardt,D., Pijnenburg,Y., Rascovsky, K., Williams, M.M., Yokoyama, J.S., Alladi, S., … & ISTAART FTD PIA and ISTAART Diversity and Disparities PIA. (2023). Gaps in clinical research in frontotemporal dementia: A call for diversity and disparities–focused research. Alzheimer’s & Dementia.

5. Llibre‐Guerra, J. J., Heavener, A., Brucki, S. M. D., Marante, J. P. D., Pintado‐Caipa, M., Chen, Y., Behrens, M.I., Hardi, A., Admirall-Sanchez, A., Akinyemi,R., Alladi, S., … & Diversity and Disparity Professional Interest Area Increasing Sustained Diversity in Clinical Trials Working Group. (2023). A call for clinical trial globalization in Alzheimer’s disease and related dementia. Alzheimer’s & Dementia.

6. Krishna, G., Santhoshkumar, R., Sivakumar, P. T., Alladi, S., Mahadevan, A., Dahale, A. B., … & Subramanian, S. (2023). Pathological (dis) similarities in neuronal exosome-derived synaptic and organellar marker levels between Alzheimer’s disease and frontotemporal dementia. Journal of Alzheimer’s Disease, 94(s1), S387-S397.

7. Alladi S., Rajagopalan J., Hurzuk S., Comas-Herrera A., Weidner W., Knapp M. (2022) Executive Summary. The dementia care landscape in India. STRiDE Desk Review. CPEC, London School of Economics and Political Science, London.

8. Maestre, G., Carrillo, M., Kalaria, R., Acosta, D., Adams, L., Adoukonou, T., … Alladi, S.,……& The African Dementia Consortium. (2023, March 11). The Nairobi Declaration—Reducing the burden of dementia in low‐ and middle‐income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs. Alzheimer’s & Dementia. Wiley. http://doi.org/10.1002/alz.13025

9. Llibre‐Guerra JJ, Heavener A, Brucki SMD, Marante JPD, Pintado‐Caipa M, Chen Y,….. … Alladi, S.,… & Diversity and Disparity Professional Interest Area Increasing Sustained Diversity in Clinical Trials Working Group. (2023). A call for clinical trial globalization in Alzheimer’s disease and related dementia. Alzheimer’s & Dementia. Wiley; 2023.. Available from: https://doi.org/10.1002/alz.12995

10. Singh, G., Sharma, M., Kumar, G. A., Rao, N. G., Prasad, K., Mathur, P., … Alladi, S., …..& Dandona, L. (2021). The burden of neurological disorders across the states of India: the Global Burden of Disease Study 1990–2019. The Lancet Global Health, 9(8), e1129-e1144. (Impact factor 26.7)

11. Mok VCT, Pendlebury S, Wong A, Alladi S, Au L…&, Scheltens P. Tackling challenges in care of Alzheimer’s disease and other dementias amid the COVID-19 pandemic, now and in the future. Alzheimers Dement. 2020:10.1002/alz.12143. doi: 10.1002/alz.12143. PMID: 32789951. (Impact factor 14.423)

12. Mekala S, Paplikar A, Mioshi E, Kaul S, Divyaraj G…&, Alladi S. Dementia Diagnosis in Seven Languages: The Addenbrooke’s Cognitive Examination-III in India. Arch Clin Neuropsychol. 2020;35:528-538. doi: 10.1093/arclin/acaa013. PMID: 32188967. (Impact factor 2.280)

13. Alber J, Alladi S, Bae HJ, Barton DA, Beckett LA…&, Hainsworth AH. White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities. Alzheimers Dement (N Y). 2019;5:107-117. doi: 10.1016/j.trci.2019.02.001. PMID: 31011621. (Impact factor 14.423)

14. Iyer GK, Paplikar A, Alladi S, Dutt A, Sharma M…&, Varghese F; ICMR Neurocognitive Tool Box Consortium. Standardising Dementia Diagnosis Across Linguistic and Educational Diversity: Study Design of the Indian Council of Medical Research-Neurocognitive Tool Box (ICMR-NCTB). J Int Neuropsychol Soc. 2020;26:172-186. doi: 10.1017/S1355617719001127. PMID: 31826780. (Impact factor 3.098)

15. Alladi S, Hachinski V. World dementia: One approach does not fit all. Neurology. 2018 ;91:264-270. doi: 10.1212/WNL.0000000000005941. PMID: 29997191. (Impact factor 8.055)

16. Kalkonde YV, Alladi S, Kaul S, Hachinski V. Stroke Prevention Strategies in the Developing World. Stroke. 2018;49:3092-3097. doi: 10.1161/STROKEAHA.118.017384. PMID: 30571438. (Impact factor 6.032)

17. Kaul S, Alladi S, Jabeen SA, Bandaru VCSSR, Ankem U…&, Naik GS. Intracranial Atherosclerosis is the Most Common Stroke Subtype: Ten-year Data from Hyderabad Stroke Registry (India). Ann Indian Acad Neurol. 2018;21:209-213. doi: 10.4103/aian.AIAN_86_18. PMID: 30258264; (Impact factor 0.89)

18. ATTEND Collaborative Group. Family-led rehabilitation after stroke in India (ATTEND): a randomised controlled trial. Lancet. 2017;390:588-599. doi: 10.1016/S0140-6736(17)31447-2. PMID: 28666682. (Impact factor 60.392)

19. Alladi S, Bak TH, Mekala S, Rajan A, Chaudhuri JR…&, Kaul S. Impact of Bilingualism on Cognitive Outcome After Stroke. Stroke. 2016;47:258-261. doi: 10.1161/STROKEAHA.115.010418. PMID: 26585392. (Impact factor 6.032)

20. Alladi S, Bak TH, Duggirala V, Surampudi B, Shailaja M…&, Kaul S. Bilingualism delays age at onset of dementia, independent of education and immigration status. Neurology. 2013 ;81:1938-1944. doi: 10.1212/01.wnl.0000436620.33155.a4. PMID: 24198291. (Impact factor 8.055)

21. Alladi S, Mekala S, Chadalawada SK, Jala S, Mridula R, Kaul S. Subtypes of dementia: a study from a memory clinic in India. Dement Geriatr Cogn Disord. 2011;32:32-38. doi: 10.1159/000329862. PMID: 21832829. (Impact factor 2.31)

22. Alladi S, Xuereb J, Bak T, Nestor P, Knibb J…&, Hodges JR. Focal cortical presentations of Alzheimer’s disease. Brain. 2007;130:2636-2645. doi: 10.1093/brain/awm213. PMID: 17898010. (Impact factor 11.337)

23. Alladi S, Arnold R, Mitchell J, Nestor PJ, Hodges JR. Mild cognitive impairment: applicability of research criteria in a memory clinic and characterization of cognitive profile. Psychol Med. 2006 ;36:507-515. doi: 10.1017/S0033291705006744. PMID: 16426486. (Impact factor: 5.641)